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HOMELabwareUpCell

UpCell

Temperature-responsive cell cultureware for "Cell-sheet" engineering
Key features Advantages Applications Usage Specifications

Key features

outline

UpCell
UpCell
  • Collect cultured confluent cells as an intact cell-sheet without enzyme treatment.
  • Harvested cell-sheet retains intact basal membranes such as extra cellular matrix (fibronectin, laminin, collagen type IV)
  • No suture required for transplantation since fibronectin is kept intact on cells.
  • Construction of multiple layered cell-sheet is possible since fibronectin is kept intact on cells.

Key features of UpCell

  • Temperature-responsive polymer (PIPAAm) is immobilized to the surface of the cell cultureware at nano-thickness.
  • The polymer grafted surface shows reversible hydrophobic - hydrophilic property across the threshold temperature of 32℃, allowing cells to datech in a form of thin film (cell-sheet) WITHOUT harmful enzymes (e.g. trypsin or dispase).
  • The polymer is covalently bonded to the surface therefore harvested cell-sheet is free from polymer contamination.